Oral contraceptives and liver function

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Oral contraceptives and liver function

SYNOPSIS Oral contraceptives can cause liver damage and jaundice but this is very rare in women in the United Kingdom. The drugs are contraindicated where there is a history of recurrent intrahepatic cholestasis of pregnancy and acute or chronic disturbance of liver function which can be congenital or acquired. It is not yet known whether the oestrogenic or progestogenic components of oral cont...

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Oral contraceptives after liver disease.

Administration of oral contraceptives to 10 women was started two weeks after the normalization of the serum enzyme activities in the convalescent period of viral hepatitis, and to five women eight weeks after an operation of obstructive jaundice. Routine liver function tests were performed at intervals of two weeks for two to three months. The liver function tests stayed within normal limits d...

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Oral Contraceptives Use and Liver Cancer Risk

Studies about the association between oral contraceptives use and liver cancer risk have generated controversial results. Therefore, a meta-analysis of cohort and case-control studies was performed to quantitatively summarize the existing evidence.Eligible studies were identified by a computer search of PubMed and Embase databases and handed-search of reference lists, without any limitations. S...

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Effect of oral contraceptives on respiratory function.

The present study was carried out to assess the lung functions in oral contraceptive administered women. Lung function tests were carried out with Spirometer (Vitallograph Compact II). A significant increase in vital capacity (VC) was observed in these women as compared to normal control. There was also a significant decrease in forced expiratory volume in 1 sec./vital capacity (FEV1/VC%) and f...

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Liver tumors and oral contraceptives: pathology and pathogenesis.

Since 1973, over 200 cases of liver masses associated with oral contraceptive usage have been reported. Nearly 100 have been liver cell adenomas and 11 have been hepatocellular carcinomas. Focal nodular hyperplasia (FNH) appears only coincidentally associated, but with a particular hemorrhagic tendency. Bile duct proliferation distinguishes FNH from liver cell adenoma. Two typical cases are pre...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1969

ISSN: 0021-9746

DOI: 10.1136/jcp.s1-3.1.1